Post-mitotic neurons do exhibit Side Chair DNA methylation changes, contrary to the longstanding belief that the epigenetic pattern in terminally differentiated cells is essentially unchanged.While the mechanism and physiological significance of DNA demethylation in neurons have been extensively elucidated, the occurrence of de novo DNA methylation
Integrated Multiomic Analysis Reveals the High-Fat Diet Induced Activation of the MAPK Signaling and Inflammation Associated Metabolic Cascades via Histone Modification in Adipose Tissues
BackgroundThe number of diet induced obese population is increasing every year, and the incidence of type 2 diabetes is also on the rise.Histone methylation and acetylation have been shown to be associated with lipogenesis and obesity by manipulating gene expression via the formation of repression or activation domains on chromosomes.ObjectiveIn th
MENGAPA PERUSAHAAN MELAKUKAN AUDITOR SWITCH?
The existence of a large number of accounting firms allowsprovides companies choices whether to stay with current firm or switchto another accounting firm.Decision of Minister of FinanceNo.423/KMK.06/2002 states that a company must switch auditor Custom Framing afterfive years of consecutive assignment.This is mandatory.The questionrises when a com
Molecular Detection of Inducible Clindamycin Resistance among Staphylococcal Strains Isolated from Hospital Patients
Background & Objectives: Macrolide, lincosamide and streptogramin B (MLSB) antimicrobial agents are used in the treatment of staphylococcal infections.They prevent the microbial protein synthesis system through binding to 23 S rRNA.The aim of this study was to apply molecular Glass nail file methods to detect inducible clindamycin resistance genes